be aware that colour change and hair loss can be a symptom of hypothyroidism, common in dogs especially spaniels an even more common in spaniels over the age of 6, may not be, but many(most) vet overlook this despite it being responsible for many problems such as weight gain, anxiety, lack of energy, hair loss,, ear/skin infections etc etc, I might add that many dogs will have only the odd symptom not nes all of them, my dog was just lethargic...and she is now on thyroid tablets