Have to admit, I'd not heard about it before I got my Odie and Archie. It didn't seem to be one of the things to look out for or be aware of when searching for a pup. With hindsight, not sure if their higher COI's had any bearing on their problems (Odie 11.9%, Archie 16.8%). Monty's is 3.2% and I checked the COI out before I got him. It wasn't the deciding factor however, although I was pleased it was fairly low, his upbringing, family life, health checks and mother's temperament were more important.