The loss of the litter had nothing to do with the pedigree. THere are so many other factors that go into a pregnancy and whelping, and pregnancy can be precarious, no matter what. Closely inbred pups can survive and outcrosses perish, the bloodlines mean nothing here.
It depends on what you want to accomplish with your planned breeding. If you do have an established line, you would need to research very carefully other lines to see what they are producing and what they can add to your breeding program. Outcrossing with no other goal other than to inject new blood is useless, IMO, without a long term plan. Talk to breeders who have your same lines and ask what has worked and not worked as far as outcrosses. Sometimes there is what is called a "nick", two bloodlines that when merged produce very well together. And sometimes the reverse is true, so you can't go into it blindly.
Assuming that health testing and temperment are first priority and all those boxes are ticked, what I would look for is a well proven older stud dog who is consistently producing the type you are looking for and can also enhance or improve on where your bitch may be weaker. Just breeding by pedigee alone will not give you what you need, and especially in the case of outcrosses your results (puppies) will be very inconsistent in terms of quality. You also need to go type to type.
That said, if this is the first breeding for this bitch, I would suggest doing a linebreeding first, as you don't know what she produces, so you don't know yet what it is you want to correct or enhance. A linebreeding would give you this information, where an outcross would really tell you nothing. Then you could do an outcross, and then weave back into your line with subsequent generations.
Is your bitch show or working? Are you breeding for the show ring, field or other competition?
