I use Virbac enzymatic toothpaste, and a human toothbrush. I brush them every morning, a pea size bit on the brush, once for each side of the mouth. Dylan is ten now, and his teeth are white and healthy, and no dental treatment has been required at all. He is the first dog I've cleaned teeth for, it's made a lot of difference, my old dog had several teeth removed when old, and they did get tartar. I started doing Dylan's from a puppy, so part of his daily groom.