I find a wide-toothed comb is much more effective than a brush to be honest, even with a slicker I find they just skim the surface whereas a comb really gets in there and deals with knots! We also buy detangling spray made by Groomers (Pets at Home sell it too) which is very good for easing out knots.
Morgan gets walked daily in the woods and gets incredibly messy so I do my grooming after we get home and he stays tidy until the next day. He has spaniel bowls so his ears don't dangle in food or water and get sticky. They get dreadfully sticky though if he has a peanut butter Kong