sorry abit of a late reply on this topic! I use Advocate on Jasper, when I used it a couple of weeks ago he was really off, not himself at all and totally off his food for 24 hours after I had used it.
The month before when I used it I stupidly put his collar back on before it had dried properly and it took all of the colour off his leather collar, which worries as if it can do that to a collar what is it doing to him skin?
I never used any of this stuff on my old cocker and he only ever got fleas once, I am now not sure if I should not bother with the flee treatment and just worm him or swap to Frontline and see how he gets on with that, Jasper is only 7 months at the moment, I think vets push this stuff too much really and do does really need flea treatment once a month?